We show our work.
All of it.
A structured library of the studies behind hyperbaric medicine — the strong, the mixed, and the disappointing. Every condition page links here; nothing gets hidden.
12 study results shown
-
Hyperbaric treatment for decompression sickness: current recommendations
POSITIVEMoon RE · Undersea & Hyperbaric Medicine · 2019
Reviews the physiological basis and established use of recompression (e.g., US Navy Treatment Table 6) as definitive therapy for decompression sickness, the historical foundation of hyperbaric medicine.
Review -
Hyperbaric oxygen therapy for sudden sensorineural hearing loss: a meta-analysis
POSITIVERhee TM, Hwang D, Lee JS, et al. · JAMA Otolaryngology–Head & Neck Surgery · 2018
Meta-analysis found HBOT, particularly combined with steroids and started early, was associated with greater hearing recovery in idiopathic sudden sensorineural hearing loss.
Meta-analysis / review -
Hyperbaric oxygen therapy for post-concussion syndrome: contradictory conclusions from a controlled trial
POSITIVEHarch PG, Andrews SR, Fogarty EF, et al. · Medical Gas Research · 2017
Reported improvements in post-concussive symptoms and cognition with HBOT, while noting the field's ongoing controversy over sham-pressure control groups also improving.
Randomized trial n = 63 -
Hyperbaric oxygen therapy for necrotizing soft tissue infections: a systematic review
POSITIVEDevaney B, Frawley G, Frawley L, Pilcher DV · Anaesthesia and Intensive Care · 2015
Systematic review reporting associations between adjunctive HBOT and reduced mortality in necrotizing soft tissue infections, while noting the absence of randomized trials.
Review -
Hyperbaric oxygen: its mechanisms and efficacy
POSITIVEThom SR · Plastic and Reconstructive Surgery · 2011
Widely cited review of HBOT mechanisms: raised dissolved oxygen, stem/progenitor cell mobilization, angiogenesis, and effects on inflammation and reperfusion injury.
Review -
Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes (HODFU study)
POSITIVELöndahl M, Katzman P, Nilsson A, Hammarlund C · Diabetes Care · 2010
In this randomized, double-blind, placebo-controlled trial, adding HBOT to standard wound care significantly improved complete healing of chronic diabetic foot ulcers at one year versus placebo (hyperbaric air).
Randomized trial n = 94 -
Hyperbaric oxygen treatment of chronic refractory radiation proctitis
POSITIVEClarke RE, Tenorio LM, Hussey JR, et al. · International Journal of Radiation Oncology Biology Physics · 2008
Double-blind randomized trial showing HBOT significantly improved healing responses in chronic refractory radiation proctitis versus sham.
Randomized trial n = 120 -
An evidence-based appraisal of the use of hyperbaric oxygen on flaps and grafts
POSITIVEFriedman HI, Fitzmaurice M, Lefaivre JF, et al. · Plastic and Reconstructive Surgery · 2006
Appraisal concluding HBOT improves salvage of compromised (but not primarily well-perfused) skin grafts and flaps, supporting its FDA-recognized use in this setting.
Review -
Hyperbaric oxygen for acute carbon monoxide poisoning
POSITIVEWeaver LK, Hopkins RO, Chan KJ, et al. · New England Journal of Medicine · 2002
Randomized trial in which three HBOT sessions reduced the rate of cognitive sequelae at 6 weeks after acute CO poisoning compared with normobaric oxygen.
Randomized trial n = 152 -
Hyperbaric oxygen therapy in the management of crush injuries: a randomized double-blind placebo-controlled trial
POSITIVEBouachour G, Cronier P, Gouello JP, et al. · Journal of Trauma · 1996
Small double-blind RCT showing improved wound healing and fewer additional surgical procedures with HBOT in severe crush injuries, especially in older patients and severe wounds.
Randomized trial n = 36 -
Adjunctive systemic hyperbaric oxygen therapy in treatment of severe prevalently ischemic diabetic foot ulcer
POSITIVEFaglia E, Favales F, Aldeghi A, et al. · Diabetes Care · 1996
Randomized trial in which adjunctive HBOT was associated with a significantly lower rate of major amputation in patients with severe ischemic diabetic foot ulcers.
Randomized trial n = 70 -
A new concept in the treatment of osteoradionecrosis
POSITIVEMarx RE · Journal of Oral and Maxillofacial Surgery · 1985
Established the protocol combining HBOT with surgery for osteoradionecrosis of the jaw, demonstrating markedly improved resolution versus antibiotics alone and defining the modern staged approach.
Cohort study n = 268