RANDOMIZED CONTROLLED TRIAL
OUTCOME: POSITIVE
Adjunctive systemic hyperbaric oxygen therapy in treatment of severe prevalently ischemic diabetic foot ulcer
Faglia E, Favales F, Aldeghi A, et al.
Diabetes Care · 1996 · n = 70
What it found
Randomized trial in which adjunctive HBOT was associated with a significantly lower rate of major amputation in patients with severe ischemic diabetic foot ulcers.
Our note on quality
Early randomized evidence for limb salvage; unblinded.
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