COHORT STUDY
OUTCOME: POSITIVE
A new concept in the treatment of osteoradionecrosis
Marx RE
Journal of Oral and Maxillofacial Surgery · 1985 · n = 268
What it found
Established the protocol combining HBOT with surgery for osteoradionecrosis of the jaw, demonstrating markedly improved resolution versus antibiotics alone and defining the modern staged approach.
Our note on quality
Foundational clinical work; the basis of the "Marx protocol" still used today.
Summaries are plain-English paraphrases for education and may simplify nuance — always consult the original source and a physician. See our medical disclaimer.