LESSON 1
Which patients to refer
The clearest referrals are the FDA-recognized indications: chronic diabetic lower-extremity wounds (Wagner III+ unresponsive to 30 days of standard care), delayed radiation injury, refractory osteomyelitis, compromised grafts/flaps, sudden sensorineural hearing loss (time-sensitive), and the emergency indications. Off-label requests should be framed honestly with the patient about evidence and self-pay. Our referral tool assesses indication strength and drafts a letter.